I’m using enet and Bullet in a 3D FPS and it integrates nicely, though I’m using C++ and what I have at the moment is pretty basic. I guess could use pyenet if you want to go the python route with enet. I found Pandas network API’s much nicer to be honest, you don’t have to pack and unpack your packets and such. But it lacks features that enet has.
Cheers,